Description: Molecular Switch : Signaling and Allostery, Hardcover by Phillips, Rob, ISBN 0691200246, ISBN-13 9780691200248, Brand New, Free shipping in the US
A signature feature of living organisms is their ability to carry out purposeful actions by taking stock of the world around them. To that end, cells have an arsenal of signaling molecules linked together in signaling pathways, which switch between inactive and active conformations. The Molecular Switch articulates a biophysical perspective on signaling, showing how allostery—a powerful explanation of how molecules function across all biological domains—can be reformulated using equilibrium statistical mechanics, applied to diverse biological systems exhibiting switching behaviors, and successfully unify seemingly unrelated phenomena.
Rob Phillips weaves together allostery and statistical mechanics via a series of biological vignettes, each of which showcases an important biological question and accompanying physical analysis. Beginning with the study of ligand-gated ion channels and their role in problems ranging from muscle action to vision, Phillips then undertakes increasingly sophisticated case studies, from bacterial chemotaxis and quorum sensing to hemoglobin and its role in mammalian physiology. He looks at G-protein coupled receptors as well as the role of allosteric molecules in gene regulation. Phillips concludes by surveying problems in biological fidelity and offering a speculative chapter on the relationship between allostery and biological Maxwell demons.
Appropriate for graduate students and researchers in biophysics, physics, engineering, biology, and neuroscience, The Molecular Switch presents a unified, quantitative model for describing biological signaling phenomena.
Price: 105.59 USD
Location: Jessup, Maryland
End Time: 2024-12-02T19:57:16.000Z
Shipping Cost: 0 USD
Product Images
Item Specifics
Return shipping will be paid by: Buyer
All returns accepted: Returns Accepted
Item must be returned within: 14 Days
Refund will be given as: Money Back
Return policy details:
Book Title: Molecular Switch : Signaling and Allostery
Number of Pages: 440 Pages
Publication Name: Molecular Switch : Signaling and Allostery
Language: English
Publisher: Princeton University Press
Subject: Nanoscience, Life Sciences / Molecular Biology, Life Sciences / Biophysics, Physics / Atomic & Molecular
Publication Year: 2020
Item Height: 1.3 in
Item Weight: 60.2 Oz
Type: Textbook
Author: Rob Phillips
Subject Area: Science
Item Length: 10 in
Item Width: 8.4 in
Format: Hardcover
